２０１５年３月２７日 Prof. Matthew Turner & Prof. Pierre Sens （終了）

日時： ２０１５年３月２７日（金）
場所： 首都大学東京　８号館３００号室

１５：００〜１６：３０
講師： Prof. Matthew Turner (Warwick University)
題目： From animal to thermodynamic swarms
要旨： We identify an analogy between thermophoretic colloids that are heated by a focussed external light source and swarms of animals, revealing a previously unidentified connection between these two systems. The controlling interactions in animal swarms are still not well understood. Some authors have proposed interactions that are local in space, either in a metric-based or topological sense. We discuss the evidence for non-local interactions and suggest a natural choice for these that is consistent with the cognitive limitations of a bird's vision. We study this model and the various phenotypes that emerge from it before presenting supporting experimental data and making a comparison with thermodynamic systems.

１６：３０〜１８：００
講師： Prof. Pierre Sens (Institut Curie)
題目： Out-of-equilibrium membrane physics and cellular organelles
要旨： Most molecules secreted or internalized by Eukaryotic cells follow well defined routes, the secretory and endocytic pathways, along which they are exposed to a succession of biochemical environments by sequentially visiting different membrane-bound organelles. Molecules internalized by endocytosis move from early to late endosomes before being sorted and carried to their final destination. Molecules synthesized in the endoplasmic reticulum go through the Golgi apparatus, itself divided into cis, medial and trans compartments (called cisternae), where they undergo post-transcriptional maturation and sorting. One fundamental issue underlying the organization and regulation of intracellular transport is whether progression along the transport pathways occurs by exchange between organelles of fixed biochemical identities (via the budding and scission of carrier vesicles), or by the biochemical maturation of the organelles themselves. In this talk, I will present some aspects of the Physics of out-of-equilibrium membrane system, and discuss their relevance to intra-cellular transport. I will particularly focus on the dynamical coupling between biochemical maturation and phase separation of membrane components, and its possible relevance for the generation and maintenance of the Golgi apparatus.