２０１５年７月２７日 Dr. Jean Wolff （終了）

日時： ２０１５年７月２７日（月）１１：００〜１２：３０
場所： 首都大学東京　８号館３０４号室　
講師： Dr. Jean Wolff（Institut Charles Sadron）
題目： Budding of domains in mixed bilayer membranes

要旨： We propose a model that accounts for budding behavior of domains in lipid bilayers, where each of the bilayer leaflets has a coupling between its local curvature and local lipid composition. The compositional asymmetry between the two monolayers leads to an overall spontaneous curvature. The membrane free energy contains three contributions: bending energy, line tension, and a Landau free-energy for a lateral phase separation. Within a mean-field treatment, we obtain various phase diagrams which contain fully-budded, dimpled and flat states. In particular, for some range of membrane parameters, the phase diagrams exhibit a tricritical behavior as well as three-phase coexistence region. The global phase diagrams can be divided into three types and are analyzed in terms of the curvature-composition coupling parameter and domain size.